From my experience Photoshop’s “Save for web and devices” will give you the biggest bang for your buck.  It’ll give you the lowest file sizes with the least amount of artifacts.

However, one problem I had is that it’s difficult to resize a lot of images in bulk.  Especially if you want to compress images in sub directories.  After a lot of searching I came across this useful little snippet.  One thing – it’s only meant for .JPGs.  So any other format and you won’t be finding this so useful…but it might not be too hard to tweak.

To use this first download the script on your computer and open Photoshop.  Go to file>scripts>browse, select the script, then select the folder containing you .JPG images.

You can edit the file in notepad, dreamweaver, whatever.  To change to quality edit this line:
SaveForWeb(saveFile,90); // set quality to suit
Where 90 refers to the quality setting.

I also did some editing to this so it would also resize images before compressing them.  First find the line:
app.preferences.typeUnits = TypeUnits.PIXELS;
After it add:
doc.resizeImage(200, 133);
where 200,133 is the image size.  I think I did have some issues with stretching so check the aspect ratio beforehand.

Download the script here

These are bunch of sprite edits I’ve done for some games I used to play 🙂  Plese note, these are just edits the original artwork is not mine 🙁  The bases are either from gaiaonline or ragnarok online

MAJOR EDITS

MEDIUM EDITS

MINOR EDITS

These are a few anime wallpapers I made back in 2005~ for anime wallpaper community called Mini Tokyo.  The images are either scans or scans traced in Illustrator.

First design post is nothing too imaginative.  Thought I’d start off with something small and random I did.

It’s a red ball on a blue backdrop – yeap that’s it.  I was fiddling around with PS styles thinking of what kind of graphics may make good stock.  I never really came up with anything revolutionary and this was the end of that venture.